Biological Sciences Division
Pacific Northwest National Laboratory
PO Box 999
Richland, WA 99352
Dr. Bill Morgan is Director of Radiation Biology and Biophysics in the Biological Sciences Division. In this role, he provides scientific leadership at PNNL in the area of effects of radiation exposure to human health. Morgan is a leading researcher in the field of radiation biology and the long-term biological effects of radiation exposure. He is the Principal Investigator for the U.S. Department of Energy's Low Dose Radiation Research Program Scientific Focus Area at PNNL.
Dr. Morgan joined PNNL in 2008. Before then, he was Professor and Director of the Radiation Oncology Research Laboratory at the University of Maryland, Baltimore, as well as an Affiliate Scientist at PNNL. Before joining the University of Maryland in 1999, Morgan led radiation research laboratories at the University of California, San Francisco, and Lawrence Berkeley National Laboratory. He is a scientific representative for regulatory agencies such as the United Nations Scientific Committee on the Effects of Atomic Radiation, the International Commission on Radiological Protection, and the National Council for Radiation Protection. Dr. Morgan is also on the editorial board for Environmental and Molecular Mutagenesis and Mutation Research.
- Low dose, low dose rate radiation exposures
- Radiation-induced genomic instability
- Non-targeted effects of ionizing radiation
Education and Credentials
- D.Sc. University of Canterbury, Christchurch, New Zealand, 2003
- Ph.D. Cytogenetics, University of Canterbury, Christchurch, NZ, 1980
- M.Sc. Cytogenetics, University of Canterbury, Christchurch, NZ, 1977
- B.Sc. Botany, University of Canterbury, Christchurch, NZ, 1975
Affiliations and Professional Service
- Environmental Mutagen Society
- Radiation Research Society
- National Institutes of Health reviewer since 1994
- National Cancer Institute reviewer since 1998
- Breast Cancer Research Program reviewer 1990-1998
- International Science Foundation reviewer 1990-1996
- DOE reviewer since 1998
- Advisory committee member for
- - NIH Centers for Medical Countermeasures Against Radiation
- - National Academy of Sciences Board on Radiation Effect Research
- - National Council on Radiation Protection and Measurements
- - International Council on Radiation Protection
- - United Nations Scientific Committee on Effects of Atomic Radiation
- Morgan, W.F. and Sowa, M.B., Non-targeted bystander effects induced by ionizing radiation. Mutation Research 616, 159-164 (2007).
- Huang, L., Nickoloff, J.A., Kim, P.M. and Morgan, W.F. Targeted and non-targeted effects of low-dose ionizing radiation on delayed genomic instability in human cells. Cancer Research 67, 1099-1104 (2007).
- Durant, S.T., Paffett, K.S., Shrivastav, M., Timmins, G.S., Morgan, W.F. and Nickoloff, J.A. UV radiation induces delayed hyperrecombination associated with hypermutation in human cells. Molecular Cell Biology 26, 6047-6055 (2006)
- Kim, G.J., Fiskum, G. and Morgan, W.F. A role for mitochondrial dysfunction in perpetuating radiation induced genomic instability. Cancer Research 66, 10377-10383 (2006).
- Snyder, A.R. and Morgan, W.F., Lack of consensus gene expression changes associated with radiation-induced chromosomal instability. DNA Repair 4, 958-970 (2005).
- Huang, L., Grim, S., Smith, L.E., Kim, P.M., Nickoloff, J.A., Goloubeva, O.G. and Morgan, W.F. Ionizing radiation induces delayed hyperrecombination in mammalian cells. Molecular Cell Biology 24, 5060-5068 (2004).
- Morgan, W.F., Non-targeted and delayed effects of exposure to ionizing radiation: II. Radiation induced genomic instability and bystander effects in vivo, clastogenic factors and transgenerational effects. Radiation Research 159, 581-596 (2003).
- Morgan, W.F., Non-targeted and delayed effects of exposure to ionizing radiation: I. Radiation induced genomic instability and bystander effects in vitro. Radiation Research 159, 567-580 (2003).
- Paris, F., Perez, G.I., Haimovitz-Friedman, A., Nguyen, H., Fuks, Z., Bose, M., Ilagan, A., Hunt, P.A., Morgan, W.F., Tilly, J.L. and Kolesnick, R. Sphingosine 1-phosphate preserves fertility in irradiated female mice without propagating genomic damage in offspring. Nature Medicine 8, 901-902, (2002).
- Limoli, C.L., Kaplan, M.I., Giedzinski, E. and Morgan, W.F. Attenuation of radiation-induced genomic instability by free radical scavengers and cellular proliferation. Free Radical Biology & Medicine 31: 10-19 (2001).
- Limoli, C.L., Giedzinski, E., Morgan, W.F. and Cleaver, J.E. Polymerase n deficiency in the XP variant uncovers an overlap between the S phase checkpoint and double-strand break repair. Proceedings of the National Academy of Sciences (USA) 97, 7939-7946 (2000).