Staff information

Biography

Jean Futrell is internationally recognized for his pioneering research in mass spectrometry fundamentals. A principal focus is reaction kinetics and reaction dynamics of ions; his research initially emphasized ion-molecule reactions and now emphasizes high energy ion-neutral and ion-surface collisions. Dr. Futrell has a particular interest in development or significant modification of mass spectrometry instrumentation for specialized research purposes. These have included high-pressure chemical-ionization mass spectrometers, tandem, triple-quadruple instruments, tandem ion-cyclotron resonance mass spectrometers, and molecular beam instruments. Collision-induced dissociation of polyatomic ions and electron-transfer reaction dynamics are topics of special interest. Current research extends these concepts to ion-surface collisions of complex ions, their recoil excitation and soft-landing.

Dr. Futrell joined PNNL as the first Director of DOE's Environmental Molecular Sciences Laboratory (1998-2002) and in 2002 was appointed Battelle Fellow. From 1986-1997 he was chairman and Willis F. Harrington Professor of Chemistry, Biochemistry and Chemical Engineering at the University of Delaware. Professor of Chemistry, University of Utah, 1967-1986. Air Force officer and civilian scientist, Aerospace Research Laboratories, Wright-Patterson Air Force Base, 1959-1967.

Dr. Futrell's external research appointments have included David P. Gardner Research Fellow at the University of Utah; Visiting Fellow at the Joint Institute for Laboratory Astrophysics of the University of Colorado; Fulbright Professor of Physics at the University of Innsbruck, Austria; Scientific Exchange Visitor at the Heyrovsky Institute of Physical Chemistry, Prague; Von Humboldt scholar at the Hahn-Meitner Institute in Berlin; Professor Associe at the University of Paris; Albright and Wilson Lecturer at the University of Warwick (England); and Max Cade Visiting Professor in the Department of Physics, University of Innsbruck.

Current academic appointments include Willis F. Harrington Professor Emeritus at the University of Delaware and adjunct professorships at the University of Utah, Washington State University, University of Idaho and University of California, San Diego (pending).

Dr. Futrell is the author of more than 600 publications including over 300 refereed journal articles.

Education and Credentials

• B.S. in Chemical Engineering, Louisiana Polytechnic Institute
• M.S. and Ph.D. degrees in Physical Chemistry, University of California (Berkeley)

Affiliations and Professional Service

• Fellow of the American Physical Society, the American Association for Advancement of Science, and the World Innovation Foundation
• Past Chair of the American Society for Testing Materials Subcommittee II (Fundamental Studies in Mass Spectrometry)
• Past Chair of the American Society for Mass Spectrometry
• Past President of the Council for Chemical Research
• Member, American Chemical Society, American Institute of Physics, and Sigma X

Awards and Recognitions

• Designated by the Board of Directors of the American Society for Mass Spectrometry as a pioneer in his field, 2011
• Fellow of the American Chemical Society, American Physical Society, the American Association for Advancement of Science, and the World Innovation Foundation
• FH Field and JL Franklin Award for Outstanding Achievement in Mass Spectrometry by the American Chemical Society in Mass Spectrometr, 2007
• Honor issue of International Journal of Mass Spectrometry and Ion Physics, 2007
• German Mass Spectrometry Society's Wolfgang Paul Distinguished Lecturer, 2007
• PNNL Director's Award for Lifetime Achievement in Science and Technology, 2006
• First American honored by special issue of the European Journal of Mass Spectrome-try and Honor Symposium in Konstanz, Germany, 2004
• Erwin Schroedinger Gold Medal, International Symposium on Atomic and Surface Physics, 2000
• American Chemical Society Delaware Section Research Award, 1995
• University of Delaware College of Arts and Science Distinguished Scholar Award, 1997
• Alfred P. Sloan Fellow (1968-72)
• NIH Career Development Award (1969-74)

PNNL Publications

2012

• Tolmachev AV, EW Robinson, RD Smith, FE Leach, III, JH Futrell, and L Pasa-Tolic. 2012. "A Conceptual Approach for FT-ICR cell Harmonization Utilizing External Shim Electrodes ." International Journal of Mass Spectrometry 325-327:45-50.  doi:10.1016/j.ijms.2012.06.027
• Tolmachev AV, EW Robinson, S Wu, RD Smith, JH Futrell, and L Pasa-Tolic. 2012. "Angular Averaged Profiling of the Radial Electric Field in Compensated FTICR Cells." Journal of the American Society for Mass Spectrometry 23(7):1169-1172.  doi:10.1007/s13361-012-0395-x

2011

• Campbell CT, AK Datye, GA Henkelman, RF Lobo, WF Schneider, LD Spicer, WT Tysoe, JM Vohs, DR Baer, DW Hoyt, S Thevuthasan, KT Mueller, CM Wang, NM Washton, I Lyubinetsky, RG Teller, A Andersen, N Govind, K Kowalski, BC Kabius, H Wang, AA Campbell, WA Shelton, EJ Bylaska, CHF Peden, Y Wang, DL King, MA Henderson, RJ Rousseau, J Szanyi, Z Dohnalek, D Mei, BC Garrett, D Ray, JH Futrell, J Laskin, DL DuBois, LR Kuprat, and C Plata. 2011. EMSL and Institute for Integrated Catalysis (IIC) Catalysis Workshop. PNNL-20426, Pacific Northwest National Laboratory, Richland, WA. 

2010

• Futrell JH, and J Laskin. 2010. "Surface Ionization and Soft Landing Techniques in Mass Spectrometry." In Encyclopedia of Spectroscopy and Spectrometry, 2nd Edition, ed. JC Lindon, GE Tranter and DW Koppenaal, pp. 2778-2787.  Elsevier Science & Technology Books, Amsterdam, Netherlands. 

2009

• Hadjar O, P Wang, JH Futrell, and J Laskin. 2009. "Effect of the Surface on Charge Reduction and Desorption Kinetics of Soft Landed Peptide Ions." Journal of the American Society for Mass Spectrometry 20(6):901-906. 

2007

• Laskin J, JH Futrell, and IK Chu. 2007. "Is Dissociation of Peptide Radical Cations an Ergodic Process?" Journal of the American Chemical Society 129(31):9598-9599. 
• Laskin J, P Wang, O Hadjar, JH Futrell, J Alvarez, and RG Cooks. 2007. "Charge Retention by Peptide Ions Soft-Landed onto Self-Assembled Monolayer Surfaces." International Journal of Mass Spectrometry 265(1):237-243. 
• Hadjar O, JH Futrell, and J Laskin. 2007. "First Observation of Charge Reduction and Desorption Kinetics of Multiply Protonated Peptides Soft Landed onto Self-Assembled Monolayer Surfaces." Journal of Physical Chemistry C 111(49):18220-18225.  doi:10.1021/jp075293y
• Hadjar O, P Wang, JH Futrell, Y Dessiaterik, Z Zhu, JP Cowin, MJ Iedema, and J Laskin. 2007. "Design and Performance of a Novel Instrument for Soft-Landing of Biomolecular Ions on Surfaces." Analytical Chemistry 79(17):6566-6574.  doi:10.1021/ac070600h

2006

• Laskin J, TH Bailey, and JH Futrell. 2006. "Mechanisms of Peptide Fragmentation from Time-and Energy-Resolved Surface-Induced Dissociation Studies: Dissociation of Angiotensin Analogs." International Journal of Mass Spectrometry 249-250:462-472. 
• Alvarez J, JH Futrell, and J Laskin. 2006. "Soft-Landing of Peptides onto Self-Assembled Monolayer Surfaces." Journal of Physical Chemistry A 110(4):1678-1687.  doi:10.1021/jp0555044
• Fernandez F, VH Wysocki, JH Futrell, and J Laskin. 2006. "Protein Identification Via Surface-Induced Dissociation in an FT-ICR Mass Spectrometer and a Patchwork Sequencing Approach." Journal of the American Society for Mass Spectrometry 17(5):700-709. 

2005

• Laskin J, and JH Futrell. 2005. "Activation of Large Ions in FT-ICR Mass Spectrometry." Mass Spectrometry Reviews 24(2):135-167. 
• Alvarez J, RG Cooks, SE Barlow, DJ Gaspar, JH Futrell, and J Laskin. 2005. "Preparation and in situ Characterization of Surfaces Using Soft-Landing in a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer." Analytical Chemistry 77(11):3452-3460. 

2004

• Laskin J, KM Beck, JJ Hache, and JH Futrell. 2004. "Surface-Induced Dissociation of Ions Produced by Matrix-Assisted Laser Desorption Ionization in a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer." Analytical Chemistry 76(2):351-356. 
• Laskin J, TH Bailey, and JH Futrell. 2004. "Fragmentation Energetics for Angiotensin II and its Analogs from Time-and Energy-Resolved Surface-Induced Dissociation Studies." International Journal of Mass Spectrometry 234(1-3):89-99. 
• Hache JJ, JH Futrell, and J Laskin. 2004. "Relative Proton Affinities from Kinetic Energy Release Distributions for Dissociation of Proton-Bound Dimers: 2. Diamines as a Test Case." International Journal of Mass Spectrometry 233:223-231. 

2003

• Laskin J, and JH Futrell. 2003. "Collisional Activation of Peptide Ions in FT-ICR Mass Spectrometry." Mass Spectrometry Review 22:158-181. 
• Laskin J, and JH Futrell. 2003. "Energy Transfer in Collisions of Peptide Ions with Surfaces." Journal of Chemical Physics 119(6):3413-3420. 
• Laskin J, and JH Futrell. 2003. "Entropy is the Major Driving Force for Fragmentation of Proteins and Protein-Ligand Complexes in the Gas-Phase." Journal of Physical Chemistry A 107:5836-5839. 
• Laskin J, and JH Futrell. 2003. "Surface-Induced Dissociation of Peptide Ions: Kinetics and Dynamics." Journal of the American Society for Mass Spectrometry 14(12):1340-1347.  doi:10.1016/j.jasms.2003.08.004
• Laskin J, JH Futrell, and AK Shukla. 2003. "Surface-Induced Dissociation of Peptide Ions: Kinetics and Dynamics." Journal of the American Society for Mass Spectrometry 14(12):1340-1347. 
• Laskin J, T Bailey, and JH Futrell. 2003. "Shattering of Peptide Ions on Self-Assembled Monolayer Surfaces. ." Journal of the American Chemical Society 125(6):1625-1632. 
• Laskin J, TH Bailey, and JH Futrell. 2003. "Shattering of Peptide Ions on Self-Assembled Monolayer Surfaces." Journal of the American Chemical Society 125(6):1625-1632. 
• Shukla AK, and JH Futrell. 2003. ""Surface-Induced Dissociation of Acetone Cations from Self-Assembled Monolayer Surface of Flourinated Alkyl Thiol on Au (111) Substrate at Low Collision Energies"." International Journal of Mass Spectrometry 228(2-3):563-576. 
• Shukla AK, and JH Futrell. 2003. "A Beam Scattering Instrument for the Dynamics Studies of Surface-Induced Dissociation Processes." Review of Scientific Instruments 74(1):168-175. 
• Shukla AK, and JH Futrell. 2003. "Dynamics of Hyperthermal Energy Ion-Surface Collisions: Dissociative and non-dissociative Scattering of Ethanol cations from a Self-Assembled Monolayer Surface of Fluorinated Alkyl Thiol on Au (111)." International Journal of Mass Spectrometry 223(1-3):783-801. 
• Shukla AK, JH Futrell, and A Sen. 2003. "Dynamics of the Dissociative and Non-dissociative Scattering of Hyperthermal CS2+ from a Self-Assembled Fluoroalkyl Monolayer Surface on Gold Substrate." Journal of Chemical Physics 118(24):11217-11225.  doi:DOI:10.1063/1.1574311
• Bailey TH, J Laskin, and JH Futrell. 2003. "Energetics of Selective Cleavage at Acidic Residues Studied by Time-and Energy-Resolved Surface-Induced Dissociation in FT-ICR-MS." International Journal of Mass Spectrometry 222(1-3):313-327. 

2002

• Laskin J, and JH Futrell. 2002. "On the Efficiency of Energy Transfer in Collisional Activation of Small Peptides." Journal of Chemical Physics 116(10):4302-4310. 
• Laskin J, E Denisov, AK Shukla, SE Barlow, and JH Futrell. 2002. "Surface-induced dissociation in a Fourier transform ion cyclotron resonance mass spectrometer: Instrument design and evaluation." Analytical Chemistry 74:3255-3261. 
• Laskin J, EV Denisov, and JH Futrell. 2002. "Fragmentation Energetics of Small Peptides from Multiple-Collision Activation and Surface-Induced Dissociation in FT-ICR MS." International Journal of Mass Spectrometry 219(1):189-201. 
• Laskin J, EV Denisov, and JH Futrell. 2002. "Fragmentation Energetics of Small Peptides from Multiple-Collision Activation and Surface-Induced Dissociation in FT-ICR MS." International Journal of Mass Spectrometry 219:189-201. 
• Laskin J, T Bailey, EV Denisov, and JH Futrell. 2002. "On the Relative Stability of Singly Protonated des-Arg1 and des-Arg9 Bradykinins. ." Journal of Physical Chemistry A (106):9832-9836. 
• Hache JJ, J Laskin, and JH Futrell. 2002. "Relative Proton Affinities from Kinetic Energy Release Distributions for Dissociation of Proton-Bound Dimers." Journal of Physical Chemistry A 106(50):12051-12057. 

2001

• Laskin J, EV Denisov, and JH Futrell. 2001. "A Comparative Study of Collision-Induced and Surface-Induced Dissociation. II. Fragmentation of Small Alanine-Containing Peptides in FT-ICR MS. ." Journal of Physical Chemistry B 105(9):1895-1900. 

2000

• Laskin J, EV Denisov, and JH Futrell. 2000. "A Comparative Study of Collision-Induced and Surface-Induced Dissociation. I Fragmentation of Protonated Dialanine." Journal of the American Chemical Society 122(40):9703-9714. 
• Futrell JH. 2000. "Development of tandem mass spectrometry: one perspective." International Journal of Mass Spectrometry 200(1-3):495-508. 
• Laskin J, and JH Futrell. 2000. "Internal Energy Distributions Resulting from Sustained Off-Resonance Excitation in Fourier Transform Ion Syclotron Resonance Mass Spectrometry.II. Fragmentation of the 1-Bromonaphthalene Radical Cation ." Journal of Physical Chemistry A 104(23):5484-5494. 
• Laskin J, and JH Futrell. 2000. "The Theoretical Basis of the Kinetic Method from the point of View of Finite Heat Bath Theory." Journal of Physical Chemistry A 104(38):8829-8837. 
• Shukla AK, and JH Futrell. 2000. "Tandem Mass Spectrometry: Dissociation of Ions by Collisional Activation." Journal of Mass Spectrometry 35(9):1069-1090. 
• Tolmachev AV, TM Kim, HR Udseth, RD Smith, TH Bailey, and JH Futrell. 2000. "Simulation-Based Optimization of the Electrodynamic Ion Funnel for High Sensitivity Electrospray Ionization-Mass Spectrometry." International Journal of Mass Spectrometry 203(1-3):31-47. 
• Kim TM, AV Tolmachev, R Harkewicz, DC Prior, GA Anderson, HR Udseth, RD Smith, TH Bailey, VS Rakov, and JH Futrell. 2000. "Design and Implementation of a New Electrodynamic Ion Funnel." Analytical Chemistry 72:2247-2255.