Pacific Northwest National Laboratory
PO Box 999
Richland, WA 99352
Dr. Erin Baker is a bioanalytical chemist with 12 years experience utilizing ion mobility spectrometry in conjunction with mass spectrometry (IMS-MS) to study biological systems. Her research involves the development and evaluation of high-throughput LC-IMS-MS analyses to quickly study numerous samples in a short time period without losing valuable biological information. Dr. Baker's technical background includes evaluating short LC gradients for use with IMS-MS in proteomic analyses, as well as studying the number and quality of features detected with LC-IMS-MS and comparing them to existing LC-MS and LC-MS/MS instruments such as the LTQ-Orbitrap and LTQ Orbitrap Velos.
- Separation and dynamic range enhancement of peptides from complex plasma mixtures
- Development of HPLC methods and mass spectrometry instrumentation
- Structural variations between biological molecules in the solution, solid and gas phases
Education and Credentials
- Ph.D., Chemistry (specializing in Physical Chemistry), University of California, Santa Barbara, 2001-2005.
- B.S., Chemistry (minor in Mathematics), Montana State University, Bozeman, 1997-2001.
- Hengel SM, EA Floyd, ES Baker, R Zhao, S Wu, and L Pasa-Tolic. 2012. "Evaluation of SDS depletion using an affinity spin column and IMS-MS detection." Proteomics 12(21):3138-3142. doi:10.1002/pmic.201200168