Staff information

PNNL Publications

2013

• Su D, AK Shukla, B Chen, JS Kim, ES Nakayasu, Y Qu, UK Aryal, KK Weitz, TRW Clauss, ME Monroe, DG Camp, II, DJ Bigelow, RD Smith, RN Kulkarni, and W Qian. 2013. "Quantitative Site-specific Reactivity Profiling of S-Nitrosylation in Mouse Skeletal Muscle Using Cysteinyl Peptide Enrichment Coupled with Mass Spectrometry." Free Radical Biology & Medicine 57:68-78.  doi:10.1016/j.freeradbiomed.2012.12.010
• Tilton SC, KM Waters, NJ Karin, BJM Webb-Robertson, RC Zangar, MK Lee, DJ Bigelow, JG Pounds, and RA Corley. 2013. "Diet-Induced Obesity Reprograms the Inflammatory Response of the Murine Lung to Inhaled Endotoxin." Toxicology and Applied Pharmacology 262(2):137-148.  doi:10.1016/j.taap.2012.12.020

2011

• Xiong Y, B Chen, L Shi, JK Fredrickson, DJ Bigelow, and TC Squier. 2011. "Targeted Protein Degradation of Outer Membrane Decaheme Cytochrome MtrC Metal Reductase in Shewanella oneidensis MR-1 Measured Using Biarsenical Probe CrAsH-EDT2." Biochemistry 50(45):9738-9751.  doi:10.1021/bi200602f
• Bigelow DJ, and TC Squier. 2011. "Thioredoxin-dependent Redox Regulation of Cellular Signaling and Stress Response through Reversible Oxidation of Methionines." Molecular Biosystems 7(7):2101-2109.  doi:10.1039/C1MB05081H
• Jin H, BJM Webb-Robertson, ES Peterson, R Tan, DJ Bigelow, MB Scholand, JR Hoidal, JG Pounds, and RC Zangar. 2011. "Smoking, COPD and 3-Nitrotyrosine Levels of Plasma Proteins." Environmental Health Perspectives 119(9):1314-1320.  doi:10.1289/ehp.1103745

2010

• Tang Z, H Wu, D Du, J Wang, H Wang, W Qian, DJ Bigelow, JG Pounds, RD Smith, and Y Lin. 2010. "Sensitive Immunoassays of Nitrated Fibrinogen in Human Biofluids." Talanta 81(4-5):1662-1669. 
• Zhang X, J Zhou, MH Chin, AA Schepmoes, VA Petyuk, KK Weitz, BO Petritis, ME Monroe, DG Camp, II, SA Wood, WP Melega, DJ Bigelow, DJ Smith, W Qian, and RD Smith. 2010. " Region-Specific Protein Abundance Changes in the Brain of MPTP-induced Parkinson's Disease Mouse Model ." Journal of Proteome Research 9(3):1496-1509.  doi:10.1021/pr901024z
• Zhang X, ME Monroe, B Chen, MH Chin, TH Heibeck, AA Schepmoes, F Yang, BO Petritis, DG Camp, II, JG Pounds, JM Jacobs, DJ Smith, DJ Bigelow, RD Smith, and W Qian. 2010. "Endogenous 3, 4- Dihydroxyphenylalanine and Dopaquinone Modifications on Protein Tyrosine: links to mitochondrially derived oxidative stress via hydroxyl radical." Molecular & Cellular Proteomics. MCP 9(6):1199-1208. 

2009

• Bigelow DJ. 2009. "Nitrotyrosine-modified SERCA2: a cellular sensor of reactive nitrogen species." Pflugers Archiv: European Journal of Physiology 457(3):701-710.  doi:10.1007/s00424-007-0429-6
• Chen L, Q Yao, TA Soares, TC Squier, and DJ Bigelow. 2009. "Phospholamban Modulates the Functional Coupling between Nucleotide Domains in Ca-ATPase Oligomeric Complexes in Cardiac Sarcoplasmic Reticulum ." Biochemistry 48(11):2411-2421. 
• Yan P, T Wang, GJ Newton, TV Knyushko, Y Xiong, DJ Bigelow, TC Squier, and MU Mayer. 2009. "A Targeted Releasable Affinity Probe (TRAP) for In Vivo Photo-Crosslinking." Chembiochem 10(9):1507-1518.  doi:10.1002/cbic.200900029

2008

• Bigelow DJ, and W Qian. 2008. "Quantitative Proteome Mapping of Nitrotyrosines." In Methods in Enzymology, Nitric Oxide Part F: Oxidative and Nitrosative Stress in Redox Regulation of Cell Signaling, vol. 440, pp. 191-205.  Elsevier, Amsterdam, Netherlands. 
• Boschek CB, H Sun, DJ Bigelow, and TC Squier. 2008. "Different Conformational Switches Underlie the Calmodulin-Dependent Modulation of Caclium Pumps and Channels." Biochemistry 47(6):1640-1651.  doi:10.1021/bi701987n
• Boschek CB, TE Jones, HS Smallwood, TC Squier, and DJ Bigelow. 2008. "Loss of the Calmodulin-Dependent Inhibition of RyR1 Calcium Release Channel Upon Oxidation of Methionines in Calmodulin." Biochemistry 47(1):131-142.  doi:10.1021/bi701352w
• Chen B, JE Mahaney, MU Mayer, DJ Bigelow, and TC Squier. 2008. "Concerted but Noncooperative Activation of Nucleotide and Actuator Domains of the Ca-ATPase Upon Calcium Binding." Biochemistry 47(47):12448-12456.  doi:10.1021/bi8014289
• Chin MH, W Qian, H Wang, VA Petyuk, JS Bloom, DM Sforza, G Lacan, D Liu, AH Khan, RM Cantor, DJ Bigelow, WP Melega, DG Camp, II, RD Smith, and DJ Smith. 2008. "Mitochondrial dysfunction, oxidative stress and apoptosis revealed by proteomic and transcriptomic analyses of the striata in two mouse models of Parkinson's disease." Journal of Proteome Research 7(2):666-677.  doi:10.1021/pr070546l

2007

• Boschek CB, TC Squier, and DJ Bigelow. 2007. "Disruption of Interdomain Interactions Upon Partial Calcium Occupancy of Calmodulin ." Biochemistry 46(15):4580-4588. 
• Boschek CB, TE Jones, TC Squier, and DJ Bigelow. 2007. "Calcium Occupancy of N-terminal Sites within Calmodulin Induces Inhibition of the Ryanodine Receptor Calcium Release Channel." Biochemistry 46(37):10621-10628.  doi:10.1021/bi700655h
• Hooker BS, DJ Bigelow, and CT Lin. 2007. "Methods for Mapping of Interaction Networks Involving Membrane Proteins." Biochemical and Biophysical Research Communications 363(3):457-461. 
• Smallwood HS, NM Lourette, CB Boschek, DJ Bigelow, RD Smith, L Pasa-Tolic, and TC Squier. 2007. "Identification of a Denitrase Activity Against Calmodulin in Activated Macrophages Using High-Field Liquid Chromatography - FTICR Mass Spectrometry." Biochemistry 46(37):10498-10505. 
• Stenoien DL, TV Knyushko, MP Londono, L Opresko, MU Mayer, ST Brady, TC Squier, and DJ Bigelow. 2007. "Cellular Trafficking of Phospholamban and Formation of Functional Sarcoplasmic Reticulum During Myocyte DIfferentiation." American Journal of Physiology. Cell Physiology 292(6):C2084-2094.  doi:10.1152/ajpcell.00523.2006
• Zhang Q, W Qian, TV Knyushko, TRW Clauss, SO Purvine, RJ Moore, CA Sacksteder, MH Chin, DJ Smith, DG Camp, II, DJ Bigelow, and RD Smith. 2007. "A Method for Selective Enrichment and Analysis of Nitrotyrosine-Containing Peptides in Complex Proteome Samples." Journal of Proteome Research 6(6):2257-2268.  doi:10.1021/pr0606934

2006

• Bigelow DJ, and TC Squier. 2006. "Coil-to-Helix Transition within Phospholamban Underlies Release of Ca-ATPase Inhibition in Response to ß-Adrenergic Signaling." Current Enzyme Inhibition 2(1):19-27.  doi:10.2174/157340806775473508
• Sacksteder CA, W Qian, TV Knyushko, HH Wang, MH Chin, G Lacan, WP Melega, DG Camp, II, RD Smith, DJ Smith, TC Squier, and DJ Bigelow. 2006. "Endogenously Nitrated Proteins in Mouse Brain: Links To Neurodegenerative Disease ." Biochemistry 45(26):8009-8022.  doi:10.1021/bi060474w
• Sacksteder CA, JE Whittier, Y Xiong, J Li, NA Galeva, ME Jacoby, SO Purvine, TD Williams, MC Rechsteiner, DJ Bigelow, and TC Squier. 2006. "Tertiary Structural Rearrangements upon Oxidation of Methionine145 in Calmodulin Promotes Targeted Proteasomal Degradation." Biophysical Journal 91(4):1480-1493. 
• Xu S, J Ying, B Jiang, W Guo, T Adachi, V Sharov, H Lazar, J Menzoian, TV Knyushko, DJ Bigelow, C Schoneich, and R Cohen. 2006. "Detection of Sequence-Specific Tyrosine Nitration of Manganese SOD and SERCA in Cardiovascular Disease and Aging ." American Journal of Physiology. Heart and Circulatory Physiology 290(6):H2220-H2227. 

2005

• Knyushko TV, VS Sharov, TD Williams, C Schoneich, and DJ Bigelow. 2005. "3-Nitrotyrosine Modification of SERCA2a in the Aging Heart: A Distinct Signature of the Cellular Redox Environment ." Biochemistry 44(39):13071-81. 
• Bigelow DJ, and TC Squier. 2005. "Redox Modulation of Cellular Signaling and Metabolism Through Reversible Oxidation of Methionine Sensors in Calcium Regulatory Proteins." Biochimica et Biophysica Acta--Proteins and Proteomics 1703(2):121-134. 
• Bigelow DJ, and TC Squier. 2005. "Redox modulation of cellular signaling and metabolism through reversible oxidation of methionine sensors in calcium regulatory proteins." Biochimica et Biophysica Acta--Proteins and Proteomics 1703(2):121-134.  doi:10.1016/j.bbapap.2004.09.012
• Hulme JT, K Konoki, TWC Lin, MA Gritsenko, DG Camp, II, DJ Bigelow, and W Catterall. 2005. "Sites of Proteolytic Processing and Noncovalent Association of the Distal C-terminal Domain of CaV1.1 Channels in Skeletal Muscle." Proceedings of the National Academy of Sciences of the United States of America 102(14):5274-5279.  doi:10.1073/pnas.0409885102
• Li J, CB Boschek, Y Xiong, CA Sacksteder, TC Squier, and DJ Bigelow. 2005. "Essential Role for Pro(21) in Phospholamban for Optimal Inhibition of the Ca-ATPase ." Biochemistry 44(49):16181-16191. 

2004

• Chen B, TC Squier, and DJ Bigelow. 2004. "Calcium Activation of the Ca-ATPase Enhances Conformational Heterogeneity Between Nucleotide Binding and Phosphorylation Domains ." Biochemistry 43(14):4366-4374. 
• Li J, DJ Bigelow, and TC Squier. 2004. "Conformational Changes Within the Cytosolic Portion of Phospholamban Upon Release of Ca-ATPase Inhibition." Biochemistry 43(13):3870-3879. 

2003

• Li J, DJ Bigelow, and TC Squier. 2003. "Phosphorylation by cAMP-dependent Protein Kinase Modulates the Structural Coupling Between the Transmembrane and Cytosolic Domains of Phospholamban." Biochemistry 42(36):10674-10682. 

2002

• Chen B, and DJ Bigelow. 2002. "Phosphorylation Induces a Conformational Transition near the Lipid-Water Interface of Phospholamban Reconstituted with the Ca-ATPase ." Biochemistry 41(47):13965-13972.