Staff information

Chenghong Lei

Systems Toxicology
Scientist
Pacific Northwest National Laboratory
PO Box 999
MSIN: J4-02
Richland, WA 99352
509/371-6962
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Jin H, Y Yu, WB Chrisler, Y Xiong, D Hu, and C Lei. 2012. "Delivery of MicroR A-10b with Polylysine Nanoparticles for Inhibition of Breast Cancer Cell Wound Healing." Breast Cancer: Basic and Clinical Research 6:9-19. doi:10.4137/BCBCR.S8513
Tam TK, B Chen, C Lei, and J Liu. 2012. "In situ Regeneration of NADH via Lipoamide Dehydrogenase-catalyzed Electron Transfer Reaction Evidenced by Spectroelectrochemistry." Bioelectrochemistry and Bioenergetics 86:92-96. doi:10.1016/j.bioelechem.2012.03.002
Wen Q, X Li, B Chen, P Yao, C Lei, and J Liu. 2012. "Intramesoporous Silica Structure Differentiating Protein Loading Density." Materials Letters 75:102-106. doi:10.1016/j.matlet.2012.01.128
Yu Y, B Chen, WN Qi, X Li, Y Shin, C Lei, and J Liu. 2012. "Enzymatic Conversion of CO2 to Bicarbonate in Functionalized Mesoporous Silica." Microporous and Mesoporous Materials 153:166-170. doi:10.1016/j.micromeso.2011.12.005

Chen B, SS Shah, Y Shin, C Lei, and J Liu. 2011. "In vitro release of organophosphorus acid anhydrolase from functionalized mesoporous silica against nerve agents." Analytical Biochemistry 421(2):477-81. doi:10.1016/j.ab.2011.09.024
Gomes DE, RD Lins, PG Pascutti, C Lei, and TA Soares. 2011. "Conformational Variability of Organophosphorus Hydrolase upon Soman and Paraoxon Binding ." Journal of Physical Chemistry B 115(51):15389-15398. doi:10.1021/jp208787g

Gomes DEB, RD Lins, PG Pascutti, C Lei, and TA Soares. 2010. "The Role of Non-Bonded Interactions in the Conformational Dynamics of Organophosphorous Hydrolase Adsorbed onto Functionalized Mesoporous Silica Surfaces." Journal of Physical Chemistry B 114(1):531-540.
Lei C, P Liu, B Chen, Y Mao, HE Engelmann, Y Shin, J Jaffar, I Hellstrom, J Liu, and KE Hellstrom. 2010. "Local Release of Highly Loaded Antibodies from Functionalized Nanoporous Support for Cancer Immunotherapy." Journal of the American Chemical Society 132(20):6906-6907.

Lei C, D Hu, and EJ Ackerman. 2009. "Clay Nanoparticle-Supported Single-Molecule Fluorescence Spectroelectrochemistry." Nano Letters 9(2):655-658.
Chen B, C Lei, Y Shin, and J Liu. 2009. "Probing Mechanisms for Enzymatic Activity Enhancement of Organophosphorus Hydrolase in Functionalized Mesoporous Silica." Biochemical and Biophysical Research Communications 390(4):1177-1181. doi:10.1016/j.bbrc.2009.10.112
Hu D, C Lei, and EJ Ackerman. 2009. "Single-molecule electron transfer reactions in nanomaterials." In Microscopy and Microanalysis 2009: Proceedings, July 26-30, 2009, Richmond, Virginia, vol. 15, no. Suppl 2, ed. LN Brewer, pp. 1138-1139. Cambridge University Press, New York. doi:10.1017/S1431927609095178

Lei C, D Hu, and EJ Ackerman. 2008. "Single-molecule Fluorescence Spectroelectrochemistry of Cresyl Violet." Chemical Communications (43):5490-5492. doi:10.1039/b812161c
Lei C, TA Soares, Y Shin, J Liu, and EJ Ackerman. 2008. "Enzyme Specific Activity in Functionalized Nanoporous Supports." Nanotechnology 19(12):Art. No. 125102. doi:10.1088/0957-4484/19/12/125102

Lei C, MM Valenta, P Saripalli, and EJ Ackerman. 2007. "Biosensing Paraoxon in Simulated Environmental Samples by Immobilized Organophosphorus Hydrolase in Functionalized Mesoporous Silica ." Journal of Environmental Quality 36(1):233-238.
Lei C, Y Shin, J Liu, and EJ Ackerman. 2007. "Synergetic Effects of Nanoporous Support and Urea on Enzyme Activity." Nano Letters 7(4):1050-53. doi:10.1021/nl070255b

Lei C, Y Shin, JK Magnuson, GE Fryxell, LL Lasure, DC Elliott, J Liu, and EJ Ackerman. 2006. "Characterization of Functionalized Nanoporous Supports for Protein Confinement ." Nanotechnology 17(22):5531-5538. doi:10.1088/0957-4484/17/22/001

Lei C, Y Shin, J Liu, and EJ Ackerman. 2002. "Entrapping Enzyme in a Functionalized Nanoporous Support." Journal of the American Chemical Society 124(38):11242-3.