Welcome to the Fundamental & Computational Sciences website.
I hope you take the opportunity to explore it and learn about the outstanding people, capabilities and scientific research at the Pacific Northwest National Laboratory.
—Doug Ray, Associate Lab Director
"We strive to make progress on today's important scientific challenges."
New Project is the ACME of Addressing Climate Change
Eight national laboratories, including PNNL, are combining forces with the NCAR, four universities and one private-sector company, to start work on the most complete climate and Earth system model yet. High performance computing will be used for the Accelerated Climate Modeling for Energy project to address challenging and demanding climate change issues.
Researchers joining project to build next-generation Earth climate model
Comprehensive Proteomic Dataset of Ovarian Tumor Samples Released
One of the largest publicly available datasets for cancer researchers
A collaboration between researchers from PNNL and Johns Hopkins University has produced a comprehensive dataset of the proteomic analyses of high-grade serous ovarian tumor samples. Such tumors are the most common cancer of the ovary. The dataset provides researchers the opportunity to develop and test novel proteogenomic integration tools and algorithms to extend their understanding of cancer biology and how genomic through proteomic changes interact to drive cancer-information that can help identify clinical targets for treatment. The dataset was released June 16 by the National Cancer Institute (NCI) Clinical Proteomic Tumor Analysis Consortium (CPTAC). This is the one of the largest public datasets covering the proteome, phosphoproteome, and glycoproteome with complementary deep genomic sequencing data on the same tumor.
Playing 20 Questions with Molecules at Plasmonic Junctions
Toward engineering ultrasensitive probes of nanoscale physical and chemical processes
Sometimes, it seems as if molecules struggle to communicate with scientists. When it comes to junction plasmons, essentially light waves trapped at tiny gaps between noble metals, what the molecules have to say could radically change the design of detectors used for science and security. Single molecule detection sensitivity is feasible through Raman scattering from molecules coaxed into plasmonic junctions. Scientists at Pacific Northwest National Laboratory found that sequences of Raman spectra recorded at a plasmonic junction exhibit dramatic intensity fluctuations, accompanied by switching from familiar vibrational line spectra of a molecule to broad band spectra of the same origin. The fluctuations confirm the team's earlier model that assigns enhanced band spectra in Raman scattering from plasmonic nanojunctions to shorting of the junction plasmon through intervening molecular bridges.
This month, Dr. Alexandre Tartakovsky joins the Advanced Computing, Mathematics, and Data Division as the full-time Associate Division Director for Computational Mathematics. In his new role, Alex will oversee the talented personnel who compose ACMD Division’s Computational Mathematics group, which includes computational engineering, uncertainty quantification, multiscale mathematics, and computational social sciences teams. Alex’s goal is to continue building PNNL’s Computational Mathematics group to world-class strength. He also will continue his scientific leadership role in applied mathematics through a variety of important projects.