Welcome to the Fundamental & Computational Sciences website.
I hope you take the opportunity to explore it and learn about the outstanding people, capabilities and scientific research at the Pacific Northwest National Laboratory.
—Doug Ray, Associate Lab Director
"We strive to make progress on today's important scientific challenges."
Man trumps dog: Earlier assumption about BPA exposure confirmed
New human study shows oral exposure does not create risk for high BPA exposure
Coating the mouth with BPA-containing food, like soup, does not lead to higher than expected levels of BPA in blood, a new study in Toxicology and Applied Pharmacology shows. The study authors, including PNNL's Justin Teeguarden, conclude that oral exposure does not create a risk for high exposures.
BPA, also known as bisphenol A, is used to make some plastics and to seal canned food containers against bacterial contamination. Food, which picks up trace amounts of BPA from packaging, is the major source of human exposure.
How Ionic: Scaffolding in Charge of Calcium Carbonate Crystals
Proteins and carbohydrates may instigate crystallization by acting like a sponge to capture calcium ions
Nature packs away carbon in chalk, shells, and rocks made by marine organisms that crystallize calcium carbonate. Now, research suggests that the soft organic scaffolds in which such crystals form direct crystallization by soaking up the calcium like an "ion sponge," according to new work in Nature Materials. Using a powerful microscope that lets researchers see the formation of crystals in real time, a team led by Pacific Northwest National Laboratory found that negatively charged molecules control where, when, and how calcium carbonate forms. These large macromolecules do so by directing where calcium ions bind in the scaffold rather than by providing the best environment for the crystal, as thought previously. Understanding the process better may help researchers to design bioinspired approaches to synthesize materials with unique structural, optical, and responsive properties, interpret the ancient climate record, and figure out how to remove climate-changing carbon dioxide from the atmosphere and ocean.