June 7, 2023
Journal Article

Label-Free Profiling of up to 200 Single-Cell Proteomes per Day Using a Dual-Column Nanoflow Liquid Chromatography Platform

Abstract

Mass spectrometry-based single-cell proteomics (SCP) has great potential to inform the cellular phenotypes. The sensitivity of such measurements increases with low-flow separations (

Published: June 7, 2023

Citation

Webber K.G., T. Truong, M.S. Johnston, S. Zapata, Y. Liang, J. Davis, and A. Buttars, et al. 2022. Label-Free Profiling of up to 200 Single-Cell Proteomes per Day Using a Dual-Column Nanoflow Liquid Chromatography Platform. Analytical Chemistry 94, no. 15:6017–6025. PNNL-SA-170317. doi:10.1021/acs.analchem.2c00646

Research topics

Single cell proteomics