Programs & Projects: Macromolecular Structure and Dynamics
The Macromolecular Structure and Dynamics group includes Biological Separations & Mass Spectrometry and Structural Biology & Microimaging. Examples of current project and capabilities for both technical areas in the following categories are described here.
Advanced Methods
- High-Throughput Approach for Global Proteomic Measurements
- Nanoscale Proteomics
- Dynamic Range Enhancement Applied to Mass Spectrometry (DREAMS)
- Targeted (data-directed) LC-MS/MS
- Top-Down Proteomics with Intact Proteins
- Software/Image Generation
Production Proteomics
Environmental Applications
- Characterization of Metal Reducing Microbial Systems by High Resolution Proteomic Measurements
- Characterization of Rhodobacter sphaeroides by High-Resolution Proteomic Measurements
Biomedical Applications
- Proteomics National Center for Research Resource
- Pathogenicity Genotype Versus Phenotype
- Biomarker Discovery Initiative with the Fred Hutchinson Cancer Research Center
- High-Throughput Proteomics for Trauma Research with the Inflammation and the Host Response to Injury Consortium
- Advanced Proteomics and Metabolomics Studies of Type 1 Diabetes
- Proteomics and Metabolomics Approaches to Diagnose Diabetes and Pre-Diabetes
- Methods for Analysis and Quantification of Signal Transduction Proteins in the Yeast Pheromone Pathway
- Transcriptome and Proteome Mapping of the Mouse Brain