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Biological Sciences

Systems Toxicology

Contact: Dr. Karla Thrall

Pacific Northwest National Laboratory's Systems Toxicology Group contains research staff and facilities to deliver integrated, science-based solutions to complex health effects problems related to the environment.

The group consists of staff with a broad range of technical capabilities, providing a strong base for interdisciplinary integration within the group, as well as external to the group. Activities within the group nurture a hand-in-hand connection between experimental research and theoretical modeling.

Signature Strengths

Core Technical Capabilities

Our core technical capabilities are listed here.

  • Computational modeling
  • Whole animal imaging
  • NMR for metabolomics
  • Toxicology
  • Internal dosimetry
  • Biomonitoring

These form the basis of our Signature Strengths, which are described further here.

In addition to group research activities, we manage the Animal Resource Center for PNNL. This Resource Center contains 28 rooms dedicated to housing and caring for research animals and is AAALAC accredited.


Our wide range of industrial and government clients include

  • National Institutes of Health
  • Environmental Protection Agency;
  • Department of Energy
  • Centers for Disease Control;
  • Chemical, pharmaceutical, and consumer product firms.

Biological Sciences

Seminar Series

Fundamental & Computational Sciences

Research Highlights

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