In nature, DNA exists within a solution rife with electrostatically charged atoms or molecules called ions. A recent study led by Pacific Northwest National Laboratory researchers investigated a new model of how B-DNA, the form of DNA that predominates in cells, is influenced by the water-and-ions “atmosphere” around it.
PNNL scientists Vijay Murugesan, Jian Zhi Hu, Birgit Schwenzer, Zhenguo Yang, Theva Thevuthasan, Jun Liu, and Gordon Graff co-authored a research paper that has been named one of 25 most-cited solid-state nuclear magnetic resonance studies since 2011 by Elsevier, publisher of more than 2,000 academic journals.
Scientists at PNNL and at the University of Wisconsin-Madison recently made advances in unlocking the mystery of how to break down tough cellulose in plant matter by investigating Fibrobacter succinogenes S85, an anaerobic bacterium found in the rumen of cows and other herbivores. "Deconstructing" cellulose is the key to using biomass for the clean-energy biofuels of the future.
A team of researchers at PNNL are studying the hyporheic zone, a riverine biogeochemical hotspot, where hungry microbes may boost emissions of carbon dioxide, methane, and other greenhouse gases. Understanding what occurs when surface water and groundwater meet and mix is critical for understanding our planet's carbon cycle
PNNL toxicologists received Best Biological Modeling Paper and Top 10 Risk Assessment Abstract awards at the Society of Toxicology annual meeting in March. The paper's lead author is Rick Corley, and co-authors are Dan Einstein, Senthil Kabilan, Andrew Kuprat, Rick Jacob, Kevin Minard, Justin Teeguarden, and Chuck Timchalk. The abstract by Timchalk, Jordan Smith, Zana Carver, and Tom Weber...Read more by clicking the headline.
About The Division
Scientists within the Biological Sciences Division perform biological systems science research and develop technologies focused on how cells, cell communities, and organisms sense and respond to their environment. Our vision is to measure, predict, design, and control multi-cellular biological systems and bio-inspired solutions for energy, environment, and health.
Our investigator-initiated and multi-institutional collaborative research, unique scientific instrumentation, and national program leadership translate the latest scientific discoveries into technologies that are beneficial to the nation.
Our research has applications to energy, environment, and human health missions of the U.S. Department of Energy (DOE), the National Institutes of Health (NIH), and other federal agencies.